1251-1252
Isosteric Replacement of Acidic with Neutral Residues in Extracellular Loop-2 of the 
-Opioid Receptor Does Not Affect Dynorphin A(1-13) Affinity and Function
1253-1256
A Novel Macromolecular Prodrug Concept Exploiting Endogenous Serum Albumin as a Drug Carrier for Cancer Chemotherapy
EXPEDITED ARTICLES
1257-1263
N-3-Substituted Imidazoquinazolinones: Potent and Selective PDE5 Inhibitors as Potential Agents for Treatment of Erectile Dysfunction
ARTICLES
1264-1270
Synthesis, Conformational Analysis, and Biological Activity of C-Thioribonucleosides Related to Tiazofurin
1271-1281
Conformational Selection of Inhibitors and Substrates by Proteolytic Enzymes: Implications for Drug Design and Polypeptide Processing
1282-1292
Cyclin-Dependent Kinase Inhibition by New C-2 Alkynylated Purine Derivatives and Molecular Structure of a CDK2-Inhibitor Complex
1293-1310
Novel Benzofuran and Benzothiophene Biphenyls as Inhibitors of Protein Tyrosine Phosphatase 1B with Antihyperglycemic Properties
1311-1319
Synthesis and Anticonvulsant and Neurotoxic Properties of Substituted N-Phenyl Derivatives of the Phthalimide Pharmacophore
1320-1328
Statistical Molecular Design of Building Blocks for Combinatorial Chemistry
1329-1338
High-Affinity, Non-Peptide Agonists for the ORL1 (Orphanin FQ/Nociceptin) Receptor
1339-1349
Derivatives of (R)-1,11-Methyleneaporphine: Synthesis, Structure, and Interactions with G-Protein Coupled Receptors
1350-1358
Bis(phenazine-1-carboxamides): Structure-Activity Relationships for a New Class of Dual Topoisomerase I/II-Directed Anticancer Drugs
1359-1366
Deltorphin II Analogues with 6-Hydroxy-2-aminotetralin-2-carboxylic Acid in Position 1
1367-1379
Lipopolycationic Telomers for Gene Transfer: Synthesis and Evaluation of Their in Vitro Transfection Efficiency
1380-1397
Tyrosine Kinase Inhibitors. 17. Irreversible Inhibitors of the Epidermal Growth Factor Receptor: 4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides Bearing Additional Solubilizing Functions
1398-1408
Phosphinic Derivatives as New Dual Enkephalin-Degrading Enzyme Inhibitors: Synthesis, Biological Properties, and Antinociceptive Activities
BRIEF ARTICLES
1409-1412
Synthesis and Oral Antitumor Activity of Tetrakis(carboxylato)platinum(IV) Complexes
1413-1417
Inhibition of Protein Kinase C 
by Dequalinium Analogues: Dependence on Linker Length and Geometry
1418-1421
Protection against Oxidative Damage by Iron Chelators: Effect of Lipophilic Analogues and Prodrugs of N,N'-Bis(3,4,5-trimethoxybenzyl)ethylenediamine- N,N'-diacetic Acid (OR10141)
BOOK REVIEWS
1422-1422
[Full Article -
PDF]
1422-1422
[Full Article -
PDF]
ADDITIONS AND CORRECTIONS
1423-1426
2 Adrenoceptor Agonists as Potential Analgesic Agents. 2. Discovery of 4-(4-Imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene as a High-Affinity Ligand for the 2D Adrenergic Receptor