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PERSPECTIVES
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1-26
| Terminally Alkylated Polyamine Analogues as Chemotherapeutic Agents
Robert A. Casero, Jr. and
Patrick M. Woster
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27-35
Molecular Modeling of the GABA/GABAB Receptor Complex
Philippe Bernard,
Denis Guedin, and
Marcel Hibert
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36-46
Toward a Rational Design of Peptide Inhibitors of Ribonucleotide Reductase: Structure-Function and Modeling Studies
Bari A. Pender,
Xu Wu,
Paul H. Axelsen, and
Barry S. Cooperman
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47-57
exo-2-(Pyridazin-4-yl)-7-azabicyclo[2.2.1]heptanes: Syntheses and Nicotinic Acetylcholine Receptor Agonist Activity of Potent Pyridazine Analogues of (±)-Epibatidine
Daqing Che,
Thomas Wegge,
Milton T. Stubbs,
Gunther Seitz,
Heinrich Meier, and
Christoph Methfessel
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58-68
Synthesis, Antimalarial Activity, Biomimetic Iron(II) Chemistry, and in Vivo Metabolism of Novel, Potent C-10-Phenoxy Derivatives of Dihydroartemisinin
Paul M. O'Neill,
Alison Miller,
Laurence P. D. Bishop,
Stephen Hindley,
James L. Maggs,
Stephen A. Ward,
Stanley M. Roberts,
Feodor Scheinmann,
Andrew V. Stachulski,
Gary H. Posner, and
B. Kevin Park
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69-73
Synthesis and Evaluation of Pteroic Acid-Conjugated Nitroheterocyclic Phosphoramidates as Folate Receptor-Targeted Alkylating Agents
Gali Steinberg and
Richard F. Borch
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74-77
Antitumor Activity and Toxicity of Novel Nitroheterocyclic Phosphoramidates
Richard F. Borch,
Jiwen Liu,
Carolyn Joswig,
Raymond B. Baggs,
Daniel L. Dexter, and
Gina L. Mangold
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78-93
Synthesis and Biological Evaluation of Novel Pyrazoles and Indazoles as Activators of the Nitric Oxide Receptor, Soluble Guanylate Cyclase
David L. Selwood,
David G. Brummell,
Joanna Budworth,
Guillaume E. Burtin,
Richard O. Campbell,
Surinder S. Chana,
Ian G. Charles,
Patricia A. Fernandez,
Robert C. Glen,
Maria C. Goggin,
Adrian J. Hobbs,
Marcel R. Kling,
Qian Liu,
David J. Madge,
Sylvie Meillerais,
Kenneth L. Powell,
Karen Reynolds,
Graham D. Spacey,
Jeremy N. Stables,
Mark A. Tatlock,
Kerry A. Wheeler,
Grant Wishart, and
Chi-Kit Woo
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94-104
Novel, Nonpeptidic Cyanamides as Potent and Reversible Inhibitors of Human Cathepsins K and L
Jean-Pierre Falgueyret,
Renata M. Oballa,
Osamu Okamoto,
Gregg Wesolowski,
Yves Aubin,
Robert M. Rydzewski,
Peppi Prasit,
Denis Riendeau,
Sevgi B. Rodan, and
M. David Percival
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BRIEF ARTICLES
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105-109
Hexahydrochromeno[4,3-b]pyrrole Derivatives as Acetylcholinesterase Inhibitors
Maria L. Bolognesi,
Vincenza Andrisano,
Manuela Bartolini,
Anna Minarini,
Michela Rosini,
Vincenzo Tumiatti, and
Carlo Melchiorre
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110-114
Synthesis and Biological Evaluation of 17 -Alkoxyestra-1,3,5(10)-trienes as Potential Neuroprotectants Against Oxidative Stress
Laszlo Prokai,
Su-Min Oon,
Katalin Prokai-Tatrai,
Khalil A. Abboud, and
James W. Simpkins
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